Car rental is fairly expensive in Panama. Car rental agencies have offices at most airports, and locations in main cities. Major rental agencies include Avis, Hertz, National, Thrifty, Budget and Hilary Rent a Car. Rates generally include mandatory insurance and unlimited mileage. To rent a car, you must be 25 years of age and hold a valid driver’s license. When you accept your rental car be sure to inspect it carefully and note any damages, scratches, or missing items on the rental agreement, as you could be charged when the car is returned.
Here is some contact information for the most important car rental agencies in Panama: